453 EFFECT OF GROWTH HORMONE ON EPIDERMAL GROWTH FACTOR EXCRETION

Urinary growth hormone excretion.

Altered Expression of Epidermal Growth Factor Receptor (EGFR) in Glioma

      EGFR is a key molecule in cancer cells. EGFR signaling was shown to promote tumor cell proliferation and survival, invasion and angiogenesis and mediate resistance to treatment, including ionizing radiation in preclinical models. We extracted proteins from astrocytoma (III and IV) oligodendroglioma(IV) tumors and normal brain tissues and then evaluated the protein purity by Bradford test ...

Aging and urinary excretion of epidermal growth factor.

The aging process in man leads to some loss of kidney mass and function. The kidney produces epidermal growth factor (EGF), a polypeptide involved in the repairing process of epithelial cells. Human urine contains high concentrations of EGF, derived from its production in the kidney. It is not known if aging alters urinary EGF production in humans. This study investigates the possibility of dec...

Assessment of epidermal growth factor receptor status in glioblastomas

Objective(s): Our previous study showed that a newly designed tracer radioiodinated 6-(3-morpholinopropoxy)-7-ethoxy-4-(3'-iodophenoxy)quinazoline ([125I]PYK) is promising for the evaluation of the epidermal growth factor receptor (EGFR) status and prediction of gefitinib treatment of non-small cell lung cancer. EGFR is over-expressed and mutated also in glioblastoma. In the present study, the ...

Determination the Effects of Epidermal Growth Factor on Developmental Rates of Pre-Implantation Mouse Embryo

Purpose: To determine the effects of different doses of addition of exogenous epidermal growth factor (EGF) on development of pre-implantation mouse embryo. Materials and Methods: Mouse zygotes, two cell, 8 cell any morulae were collected from superovulated NMRI mice 24, 48, 64 and 80 hrs after hCG injection, respectively. The obtained embryos were cultured on medium alone, medium with 1, 4 an...